ABSTRACT

The purpose of the study is to evaluated risk factors, transmission routes, epidemiology, clinical features and laboratory analyses of acute hepatitis.

Sixty acute hepatitis infected cases hospitalized at the our clinic during 2007-2012 were observed retrospectively.

31 (51. 7%) of patients were male and 29 (48. 3%) female. The age range was between 16-60 and the average age was 27.07. There was a statistical meaningful difference between AVH-A and AVH-B patients age average (p<0.001) The cases mostly were detected seen in spring and autumn. HAV infected patients were found to be 41.7%, HBV infected 43.3%, HCV infected 3.3%, infections with unkown reasons 8.3%, HBV koinfected %1. 7 and otoimmune 1.7%. There was no contagious way and risk factors in 45 patients (75%). Hospitalization of the patients was between 3-32 days and it’s ovarege was 14.55. There was a statistical meaningful difference between AVH-A and hospitalization period (p=0.004). The mostly observed complaints were weakness (75%), anorexia (73.3), nause and vomiting (68.3), darkness of urine color (63.3). The frequent symptoms in physical examination were icterus (%85), hepatomegaly (88. 3%), splenomegaly (61.7%). There was no statistical meaningful difference in ALT, AST, ALP, GGT, total bilirubin, direct bilirubin these patient groups. The ALT average was 1826,77 U / I (46-5014), the AST average was 1313,02 U/I (65- 6881) and total bilirubin average was 12.30 (1.8-53).

The reason behind AVH-B ‘s being highly spread are socia-culturel values, big families, lack of hygienic conditions. The risk factors could not be found most of the patients. AVH- A and AVH-B case numbers were almost the same. AVH-A case numbers was increased and patients were infected in older ages.