ABSTRACT

Objective:

The purpose of the study is to evaluated risk factors, transmission routes, epidemiology, clinical features and laboratory analyses of acute hepatitis.

Materials and Methods:

Sixty acute hepatitis infected cases hospitalized at the our clinic during 2007-2012 were observed retrospectively.

Results:

31 (51. 7%) of patients were male and 29 (48. 3%) female. The age range was between 16-60 and the average age was 27.07. There was a statistical meaningful difference between AVH-A and AVH-B patients age average (p<0.001) The cases mostly were detected seen in spring and autumn. HAV infected patients were found to be 41.7%, HBV infected 43.3%, HCV infected 3.3%, infections with unkown reasons 8.3%, HBV koinfected %1. 7 and otoimmune 1.7%. There was no contagious way and risk factors in 45 patients (75%). Hospitalization of the patients was between 3-32 days and it’s ovarege was 14.55. There was a statistical meaningful difference between AVH-A and hospitalization period (p=0.004). The mostly observed complaints were weakness (75%), anorexia (73.3), nause and vomiting (68.3), darkness of urine color (63.3). The frequent symptoms in physical examination were icterus (%85), hepatomegaly (88. 3%), splenomegaly (61.7%). There was no statistical meaningful difference in ALT, AST, ALP, GGT, total bilirubin, direct bilirubin these patient groups. The ALT average was 1826,77 U / I (46-5014), the AST average was 1313,02 U/I (65- 6881) and total bilirubin average was 12.30 (1.8-53).

Conclusion:

The reason behind AVH-B ‘s being highly spread are socia-culturel values, big families, lack of hygienic conditions. The risk factors could not be found most of the patients. AVH- A and AVH-B case numbers were almost the same. AVH-A case numbers was increased and patients were infected in older ages.