Research Article

The Seroprevalence of HBsAg, Anti-HBs ve Anti-HCV in Patients Applied Hemodialysis in Rize Province


  • Aysegül ÇOPUR ÇİÇEK
  • Osman Zikrullah ŞAHİN
  • Mustafa Kemal TOPALOĞLU
  • İsmail Hakkı YENİLMEZ
  • Kazım ŞAHİN

Viral Hepat J 2013;19(1):15-18


Viral hepatitis is still a significant risk for both personel and patients in hemodialysis units. Initially we aimed to determine the seropositivity rates of HBsAg, Anti-HBs ve Anti-HCV in Rize province for hemodialysis patients.

Materials and Methods:

In 2011, 181 hemodialysis patients were enrolled from four different hemodialysis units in Rize province (one private and others state). Data were collected by scanning of the charts of patients retrospectively. The samples of patients were analysed for HBsAg, Anti-HBs and Anti-HCV seropositivities by ELISA method.


Mean age of 181 patients (68 women, 113 men) was 59.26 (15.02 SD) and it was 58.57 (15.81 SD) for men and 60.41 (13.64 SD) for women. The applied dialysis time to patients was 3-114 months and its mean was 57.33 (58.61 SD) in general (54.15 (56.54 SD) for men, 62.57 (61.93 SD) for women). The rates of seropositivity for HBsAg, Anti-HBs and Anti-HCV were 5.5%, 73.5% and 16.0%, respectively. HBsAg-Anti-HCV concurrent positivity was detected only one patient. There was no gender differences between sex for HBsAg or Anti-HBs or Anti-HCV seropositivities, or HBsAg and Anti-HCV concurrent positivity. Similarly, there was no significant differences for each seropositivity rate between age groups. Anti-HCV positivity was higher in patients who dialysed for a long time. HBsAg seropositivity was found to be borderline significant. It was not found any significant relation between application of dialysis and the HBsAg, Anti-HBs and Anti-HCV seropositivities.


Seroprevalence of hepatitis B and C in Rize is similar to other provinces. Nonetheless, viral hepatitis is still a major health problem for hemodialysis patients. Appropriate infection control measures, vaccination, using of erythropoietin instead of blood transfusion, and education of patients and health professionals will reduce the risk of transmission in hemodialysis patients.

Keywords: Hemodialysis, hepatitis, seroprevalencee

Full Text (Turkish)