Brief Report

HBs Ag, Anti-HBs, Anti-HBc Total and Anti-HCV Seroprevalence of the Patients Applied to Beytepe Military Hospital

10.4274/Vhd.36844

  • Mehmet ÇOBAN
  • Erdim SERTOĞLU

Viral Hepat J 2013;19(3):152-155

Objective:

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are a worldwide health problem which may result in cirrhosis and hepatocellular carcinoma. In this study, we aimed to determine the seroprevalences of hepatitis B surface antigen (HBs Ag), hepatitis B surface antibody (Anti-HBs), hepatitis B core antibody (Anti-HBc Total) and HCV antibody (Anti-HCV) in patients admitted to our hospital between June 01, 2011-May 31, 2013.

Methods:

Medical records of 11758 patients, including serological tests mentioned in the study, were evaluated retrospectively. HBs Ag, Anti-HBs, Anti HBc Total and Anti-HCV markers were analyzed by chemiluminescence immunoassay method with Architect i1000SR (Abbott, USA) autoanalyser. The study made with the permission of Gulhane Military Medical Academy local ethics committee.

Results:

When the records of 11758 patients evaluated retrospectively, there were seropositivity of HBs Ag in 298 of 11728 patients (2.54%), positivity of Anti-HBs in 1044 of 2378 patients (43.9%), positivity of Anti-HBc Total in 291 of 1256 patients (23.17%) and seropositivity of Anti-HCV in 42 of 7615 patients (0.55%). According to gender, men’s HBs Ag, anti-HBs, anti-HBc total and anti-HCV positivity rates were 2.62%, 42.22%, 24.86% and 0.57%, respectively; while women’s rates were 1.19%, 53.74%, 13.92% and 0.32%, respectively.

Conclusion:

HBsAg, anti-HBs and anti-HCV seropositivity rates which we have detected in this study were consistent with other studies conducted in in our country. Over the years there may not seen any changes as Anti-HCV seropositivity. However, because of the immunization of newborns since 1998, decrease in HBsAg positivity and increase in anti-HBs positivity are expected.

Keywords: Hepatitis B, hepatitis C, seroprevalance

Full Text (Turkish)